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acronyms&Me.

Labels and the boxes they're found on... PTSD, ADD, ADHD, OCD, BPD, RVN, UH-1, AHC, FUBAR, DOA, DILLYGAF?, SNAFU, FTA, MIA, AWOL, JAG, FIGMO, VA, BCMR, BMET, SBET, WNL, R&R, CIS, SSI, VFD, PI, AMA, FEMA, USFA, WTF?, & LOL.


COPDSeptember 16
"COPD affects more than 16 million Americans and is the fourth highest cause of death in the United States," said Robert Wise, MD, professor at the Johns Hopkins School of Medicine and director of the Hopkins SCCOR initiative. "It is the only disease among the top 10 causes of death with a rising mortality rate in the United States. It is predicted to be the third largest cause of death by 2020 and has already reached worldwide epidemic proportions."
Robt.D.McKenzie
August 13
Undergoing MyBlogLog Verification
Robt.D.McKenzie
postTraumaticStressDisorderMarch 6
For thirty years I struggled confused and alone. There wasn't much information about PTSD, so twenty or so years into my illness when I sought help I was diagnosed over a ten year span with badAttitude, drugDependence, cronicDepression, manicDepressive, biPolarDisorder, obsessiveCompulsive, schizoPhrenia, anxietyDisorder, and poorCharacter. In the mid80's I was diagnosed PTSD. I didn't have any idea what that was. At the turn of the 21st Century information started becoming available. There is no cure, but at least I understood what I'm dealing with better.

A few years ago my daughter was diagnosed add/ADHD. I was reacquainted with my son who was treated for it from the age of four or five. Then I found out my oldest daughter was being treated for biPolar. The symptoms of all these overlap such that their diagnosis is subjective relevant to the diagnostician's specialty and experiences.

My title is a link to ptsd searchResults from dogPile. The following is from a closed forumPost.

  • PTSD = quick to criticize...but not good at taking criticism!
  • PTSD = maintain a defensive posture.
  • PTSD = percieve oneself as a victim.
  • PTSD = all white or all black...all now or never...all good or all bad...all right or all wrong...etc.
  • PTSD = hypersensitive to any hint of rejection.
  • PTSD = control freak stuf






treatsGlaucomaJanuary 28

R(+)-Methanandamide and Other Cannabinoids Induce the Expression of Cyclooxygenase-2 and Matrix Metalloproteinases in Human Nonpigmented Ciliary Epithelial Cells

Susanne Rösch, Robert Ramer, Kay Brune, and Burkhard Hinz

Department of Experimental and Clinical Pharmacology and Toxicology, Friedrich Alexander University Erlangen-Nürnberg, Erlangen, Germany



how?:
Prostaglandins (PGs) and matrix metalloproteinases (MMP) havebeen implicated in lowering intraocular pressure (IOP) by facilitatingaqueous humor outflow. A possible role of cyclooxygenase-2 (COX-2)in this process was emphasized by findings showing an impairedCOX-2 expression in the nonpigmented ciliary epithelium (NPE)of patients with primary open-angle glaucoma. Using human NPEcells, the present study therefore investigated the effect ofthe IOP-lowering cannabinoid R(+)-methanandamide [R(+)-MA] onthe expression of COX-2 and different MMPs and tissue inhibitorsof MMPs (TIMPs). R(+)-MA led to a concentration- and time-dependentincrease of COX-2 mRNA expression. R(+)-MA-induced COX-2 expressionwas accompanied by time-dependent phosphorylations of p38 mitogen-activatedprotein kinase (M

medicalMarijuana cancerTreatmentJanuary 28
Breakthrough Discovered in Medical Marijuana Cancer Treatment - Salem-News.Com: "...Cancer cells that were treated with combinations of cannabinoids, antagonists of cannabinoid receptors, and small interfering ribo nucleic acid or 'siRNA' to tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) were assessed for invasiveness, protein expression, and activation of signal transduction pathways.

The biggest contribution of this breakthrough discovery, is that the expression of TIMP-1 was shown to be stimulated by cannabinoid receptor activation and to mediate the anti-invasive effect of cannabinoids.

In other words, they learned that treatment with cannabinoids, one of the active ingredients of the medicinal side of marijuana, has been shown to reduce the invasiveness of cancer cells. Prior to now the cellular mechanisms underlying this effect were unclear and the relevance of the findings to the behavior of tumor cells in vivo remains to be determined.

It is already known that marijuana can stimulate the appetite of patients, but researchers have learned that cannabinoids, in addition to having palliative benefits in cancer therapy, have been associated with anti-carcinogenic effects, which are responsible in preventing or delaying the development of cancer.

'Although the anti-proliferative activities of cannabinoids have been intensi